Infant Mice Receiving Fractionated Whole-brain Radiation Exhibit Functional Network Disorganization as Adults

Jiantao Zhu, Benjamin A. Seitzman, Franciso J. Reynoso, Timothy J. Mitchell, Annie R. Bice, Jonah A. Padawer-Curry, Xiaodan Wang, Stephanie M. Perkins, Adam Q. Bauer

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Infant (p21) mice were subjected to fractionated whole-brain radiotherapy (RT) then evaluated several months later using wide-field optical imaging. While RT broadly altered functional network organization, the largest effects occurred within higher-order cognitive regions.

Original languageEnglish
Title of host publicationOptics and the Brain, BRAIN 2024 in Proceedings Optica Biophotonics Congress
Subtitle of host publicationBiomedical Optics 2024, Translational, Microscopy, OCT, OTS, BRAIN - Part of Optica Biophotonics Congress: Biomedical Optics
PublisherOptical Society of America
ISBN (Electronic)9781957171340
DOIs
StatePublished - 2024
EventOptics and the Brain, BRAIN 2024 - Part of Optica Biophotonics Congress: Biomedical Optics - Fort Lauderdale, United States
Duration: Apr 7 2024Apr 10 2024

Publication series

NameOptics and the Brain, BRAIN 2024 in Proceedings Optica Biophotonics Congress: Biomedical Optics 2024, Translational, Microscopy, OCT, OTS, BRAIN - Part of Optica Biophotonics Congress: Biomedical Optics

Conference

ConferenceOptics and the Brain, BRAIN 2024 - Part of Optica Biophotonics Congress: Biomedical Optics
Country/TerritoryUnited States
CityFort Lauderdale
Period04/7/2404/10/24

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