Induction therapy for elderly patients with acute myeloid leukemia

Mike G. Martin, Camille N. Abboud

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Acute myeloid leukemia (AML) is a disease of older adults. Efforts to intensify therapy along traditional avenues have failed to yield improved results. There remains significant clinical equipoise as to how to "induce" patients and whether or not 7 + 3-style regimens improve outcomes over low-dose cytarabine. What is certain is that even in those not receiving active therapy, AML is an exceptionally morbid disease. Diverse interventions are being explored in the management of older patients with AML and the currently available data will be reviewed.

Original languageEnglish
Pages (from-to)311-320
Number of pages10
JournalBlood Reviews
Volume22
Issue number6
DOIs
StatePublished - Nov 1 2008

Keywords

  • Acute myeloid leukemia
  • Elderly
  • Induction therapy
  • Review

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