Inducible cardiac-specific overexpression of cyclooxygenase-2 (COX-2) confers resistance to ischemia/reperfusion injury

Keyphrases

• Overexpression 100%
• Ischemia-reperfusion Injury 100%
• Cyclooxygenase-2 100%
• Transgenic Mice 23%
• Cardioprotection 11%
• Tet-on 11%
• Tetracycline Transactivator 11%
• Therapeutic Implications 5%
• Non-associated 5%
• Apoptosis 5%
• Gene Therapy 5%
• Inflammatory Mediators 5%
• Overexpressing 5%
• Myocardial Infarction 5%
• Deleterious Effects 5%
• Reperfusion 5%
• Prostaglandin E2 5%
• Risk Areas 5%
• Infarct Size 5%
• Enzyme Activity 5%
• Genetic Tools 5%
• Protective Behavior 5%
• Myosin Heavy Chain (MyHC) 5%
• Cyclooxygenase-2 Inhibitors 5%
• Cardiac Tissue 5%
• Cardiovascular Biology 5%
• Three-line 5%
• WT Mice 5%
• Coronary Occlusion 5%
• Toxic Shock 5%
• NS-398 5%
• Late Preconditioning 5%

Biochemistry, Genetics and Molecular Biology

• Reperfusion 100%
• Cyclooxygenase 100%
• Transgenic Mouse 23%
• Enzyme 5%
• Wild Type Mouse 5%
• Genetics 5%
• Gene Therapy 5%
• Mediator 5%
• Enzyme Activity 5%
• Cross Breeding 5%
• NS-398 5%
• Programmed Cell Death 5%

Immunology and Microbiology

• Reperfusion 100%
• Cyclooxygenase 100%
• Transgenic Mouse 23%
• Mediator 5%
• Wild Type Mouse 5%
• Enzyme Activity 5%
• Cross Breeding 5%
• Programmed Cell Death 5%