Individual-level behavioral interventions to support optimal development of children with sickle cell disease: A systematic review

Catherine R. Hoyt, Sadie Hurwitz, Taniya E. Varughese, Lauren H. Yaeger, Allison A. King

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

This review aimed to identify and describe individual-level behavioral interventions for children 0–18 years of age with sickle cell disease (SCD). PRISMA guidelines were followed at each stage of this review. Twenty-seven studies were included, representing six intervention types: disease knowledge (n = 7), self-management (n = 7), pain management (n = 4), school functioning (n = 4), cognitive health (n = 4), and mental health (n = 2). Most interventions targeted older children (5+ years), while only two examined interventions for children 0–3 years. This review suggests that offering education about disease knowledge, self-management, and pain management interventions can be beneficial for this population. Future research is needed to understand interventions to support young children and the impact of SCD on development.

Original languageEnglish
Article numbere30178
JournalPediatric Blood and Cancer
Volume70
Issue number3
DOIs
StatePublished - Mar 2023

Keywords

  • child development
  • developmental delay
  • intervention
  • rehabilitation
  • sickle cell disease

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