Indications and outcomes of heart transplantation in the patient with congenital heart disease

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Abstract

The year 2008 marks the fortieth anniversary of the utilization of heart transplantation as therapy for congenital heart disease.1 Since the introduction of cyclosporine-based immunosuppression over 20 years ago,2,3 heart transplantation has evolved from a heroic therapy to a widely applied therapy for patients with congenital heart disease from infancy to adulthood. Within the International Society for Heart and Lung Transplantation (ISHLT) database, patients with congenital heart disease account for 50-75% of the transplants performed in infants <1 year of age; 25-50% of the transplants performed in children 1-10 years of age; and approximately 25% of the transplants performed in adolescents 10-17 years of age (Fig. 5.1).

Original languageEnglish
Title of host publicationHeart Failure in Congenital Heart Disease
Subtitle of host publicationFrom Fetus to Adult
PublisherSpringer London
Pages87-108
Number of pages22
ISBN (Print)9781849964791
DOIs
StatePublished - Dec 1 2011

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