TY - JOUR
T1 - Increased risk of a positive test for antibody to hepatitis B core antigen (anti‐HBC) in autologous blood donors
AU - Grossman, Brenda J.
AU - Stewart, Nadina C.
AU - Grindon, Alfred J.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - ABSTRACT: Controversy exists about the suitability of blood from autologous donors for homologous use. We compared the infectious disease test results of 426 autologous donors, designated by donor history as suitable for homologous use, to those of 86,138 volunteer donations collected over the same 5 month period. Although donor characteristics differed, the relative risk of a positive test for anti‐HBc in the autologous group was 2.09. When 413 autologous donors were compared to 413 volunteer donors matched for age, sex, and zip code, the relative risk of a positive test for anti‐HBc in the autologous group was 3.2. If anti‐HBc is a marker for non‐A, non‐B hepatitis transmissibility, then our autologous group is not as safe as our volunteer donors. We recommend that autologous blood, even when designated by donor history and laboratory screening results as suitable for homologous transfusion, not be used for other than the intended autologous recipient. 1988 AABB
AB - ABSTRACT: Controversy exists about the suitability of blood from autologous donors for homologous use. We compared the infectious disease test results of 426 autologous donors, designated by donor history as suitable for homologous use, to those of 86,138 volunteer donations collected over the same 5 month period. Although donor characteristics differed, the relative risk of a positive test for anti‐HBc in the autologous group was 2.09. When 413 autologous donors were compared to 413 volunteer donors matched for age, sex, and zip code, the relative risk of a positive test for anti‐HBc in the autologous group was 3.2. If anti‐HBc is a marker for non‐A, non‐B hepatitis transmissibility, then our autologous group is not as safe as our volunteer donors. We recommend that autologous blood, even when designated by donor history and laboratory screening results as suitable for homologous transfusion, not be used for other than the intended autologous recipient. 1988 AABB
UR - http://www.scopus.com/inward/record.url?scp=0023785357&partnerID=8YFLogxK
U2 - 10.1046/j.1537-2995.1988.28388219162.x
DO - 10.1046/j.1537-2995.1988.28388219162.x
M3 - Article
C2 - 3368940
AN - SCOPUS:0023785357
SN - 0041-1132
VL - 28
SP - 283
EP - 285
JO - Transfusion
JF - Transfusion
IS - 3
ER -