TY - JOUR
T1 - Increased Ocular and Systemic Responsiveness to Epinephrine in Primary Open-Angle Glaucoma
AU - Becker, Bernard
AU - Montgomery, Stephen W.
AU - Kass, Michael A.
AU - Shin, Dong H.
PY - 1977/5
Y1 - 1977/5
N2 - Sixteen patients with primary open-angle glaucoma (POAG) were matched as to age, sex, and race with an equal number of patients with secondary glaucoma. Although initial intraocular pressures were comparable, treatment with topical epinephrine hydrochloride, decreased intraocular pressure more than 5 mm Hg in 14 (88%) of the 16 patients with POAG but in only five (31%) of the 16 patients with secondary glaucoma (P<.005). Eleven (69%) of the 16 Patients with POAG demonstrated premature ventricular contractions during tonography as opposed to three (19%) of the 16 patients with secondary glaucoma (P<.025). These findings suggested greater ocular as well as cardiac responsiveness to epinephrine in patients with POAG.
AB - Sixteen patients with primary open-angle glaucoma (POAG) were matched as to age, sex, and race with an equal number of patients with secondary glaucoma. Although initial intraocular pressures were comparable, treatment with topical epinephrine hydrochloride, decreased intraocular pressure more than 5 mm Hg in 14 (88%) of the 16 patients with POAG but in only five (31%) of the 16 patients with secondary glaucoma (P<.005). Eleven (69%) of the 16 Patients with POAG demonstrated premature ventricular contractions during tonography as opposed to three (19%) of the 16 patients with secondary glaucoma (P<.025). These findings suggested greater ocular as well as cardiac responsiveness to epinephrine in patients with POAG.
KW - Premature ventricular contractions
KW - cyclic adenosine monophosphate
KW - epinephrine
KW - intraocular pressure
KW - primary open-angle glaucoma
KW - secondary glaucoma
UR - http://www.scopus.com/inward/record.url?scp=0017588261&partnerID=8YFLogxK
U2 - 10.1001/archopht.1977.04450050067003
DO - 10.1001/archopht.1977.04450050067003
M3 - Article
C2 - 67837
AN - SCOPUS:0017588261
SN - 0003-9950
VL - 95
SP - 789
EP - 790
JO - Archives of Ophthalmology
JF - Archives of Ophthalmology
IS - 5
ER -