Incidental pediatric intraparenchymal xanthogranuloma. Case report and review of the literature

William W. Ashley, Prithvi Narayan, Sung Park Tae, Pang Hsien Tu, Arie Perry, Jeffrey R. Leonard

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations


Juvenile xanthogranuloma (JXG) is a specialized form of non-Langerhans cell histiocyte proliferation that occurs in children. The majority of cases present as a solitary cutaneous lesion with a predilection for the head and neck region; however, isolated lesions occasionally have been identified in the central nervous system. The cutaneous forms of JXG usually follow a benign course. Other physicians have reported surgery as the first line of treatment in symptomatic patients with accessible lesions. Adjuvant therapies may be indicated for multicentric or surgically inaccessible lesions. The authors describe an unusual case of isolated intraparenchymal JXG in an asymptomatic child with no cutaneous manifestations and provide a review of the literature.

Original languageEnglish
Pages (from-to)307-310
Number of pages4
JournalJournal of neurosurgery
Issue numberSUPPL. 3
StatePublished - Apr 1 2005


  • Juvenile xanthogranuloma
  • Pediatric neurosurgery


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