Incidence, predictors and associated outcomes of renal cell carcinoma in long-term dialysis patients

Frank P. Hurst, Rahul M. Jindal, James J. Fletcher, Vikas Dharnidharka, Greg Gorman, Brent Lechner, Robert Nee, Lawrence Y. Agodoa, Kevin C. Abbott

Research output: Contribution to journalReview article

28 Scopus citations

Abstract

We carried out an analysis of the United States Renal Data System to determine the incidence, risk factors and prognosis of renal cell carcinoma (RCC) in a national population of patients receiving incident long-term dialysis. In Cox regression, male gender, older age, end-stage renal disease caused by obstruction, tuberous sclerosis, focal segmental glomerulosclerosis, as well as acquired renal cysts, were independently associated with RCC. Most cases of RCC in incident long-term dialysis patients occurred in patients without acquired renal cysts. A diagnosis of RCC was associated with increased risk of subsequent mortality overall and in all high-risk groups.

Original languageEnglish
Pages (from-to)1271-1276
Number of pages6
JournalUrology
Volume77
Issue number6
DOIs
StatePublished - Jun 1 2011
Externally publishedYes

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    Hurst, F. P., Jindal, R. M., Fletcher, J. J., Dharnidharka, V., Gorman, G., Lechner, B., Nee, R., Agodoa, L. Y., & Abbott, K. C. (2011). Incidence, predictors and associated outcomes of renal cell carcinoma in long-term dialysis patients. Urology, 77(6), 1271-1276. https://doi.org/10.1016/j.urology.2011.01.007