Inadvertent substitution of acetohexamide for acetazolamide

Newell A. Hargett, Robert Ritch, Jonathan Mardirossian, Michael A. Kass, Steven M. Podos

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


In three cases acetohexamide (Dymelor), an oral hypoglycemic agent, was mistakenly given to patients instead of acetazolamide (Diamox), which had been prescribed for their glaucoma. A number of similarities, including the-fact that both medications are 250-mg white tablets, with similar generic and brand names which are generically repackaged medications juxtaposed on the pharmacist's shelf, predispose to the inadvertent substitution of one medication for the other. In one instance a systemic hypoglycemic reaction resulting in head trauma and confusion ended in an emergency hospital admission following the substitution of acetohexamide for acetazolamide.

Original languageEnglish
Pages (from-to)580-583
Number of pages4
JournalAmerican journal of ophthalmology
Issue number4
StatePublished - Oct 1977


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