In vivo time domain speckle contrast optical spectroscopy

M. Pagliazzi, E. E. Vidal-Rosas, S. Konugolu Venkata Sekar, L. Di Sieno, L. Colombo, D. Contini, A. Torricelli, A. Pifferi, A. Dalla Mora, J. P. Culver, T. Durduran

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We propose a time domain speckle contrast optical spectroscopy (SCOS) system that makes use of a gated detector and pulsed light source to measure the blood flow variations at very short, quasi-null (<3mm) source-detector separation. We present the results of a human arm cuff occlusion and a comparison with standard SCOS, highlighting that we can probe deeper into tissue, reduce probe footprint, make efficient use of the signal and decrease cost.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO_2019
PublisherOptica Publishing Group (formerly OSA)
ISBN (Print)9781510628397
DOIs
StatePublished - 2019
EventEuropean Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands
Duration: Jun 23 2019Jun 25 2019

Publication series

NameOptics InfoBase Conference Papers
VolumePart F142-ECBO 2019
ISSN (Electronic)2162-2701

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO_2019
Country/TerritoryNetherlands
CityMunich
Period06/23/1906/25/19

Keywords

  • Speckle
  • Speckle imaging
  • Spectroscopy
  • Time-resolved imaging

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