In vivo small animal lung speckle imaging with a benchtop in-line XPC system

A. B. Garson; S. Gunsten; S. Vasireddi; S. Brody; M. A. Anastasio

doi:10.1117/12.2217267

In vivo small animal lung speckle imaging with a benchtop in-line XPC system

A. B. Garson, S. Gunsten, S. Vasireddi, S. Brody, M. A. Anastasio

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

X-ray phase-contrast (XPC) images of mouse lungs were acquired in vivo with a benchtop XPC system employing a conventional microfocus source. A strong speckled intensity pattern was present in lung regions of the XPC radiographs, previously only observed in synchroton experiments and in situ benchtop studies. We showed how the texture characteristics of the speckle is influenced by the amount of air present in the lungs at different points in the breathing cycle.

Original language	English
Title of host publication	Medical Imaging 2016
Subtitle of host publication	Physics of Medical Imaging
Editors	Despina Kontos, Joseph Y. Lo, Thomas G. Flohr
Publisher	SPIE
ISBN (Electronic)	9781510600188
DOIs	https://doi.org/10.1117/12.2217267
State	Published - 2016
Event	Medical Imaging 2016: Physics of Medical Imaging - San Diego, United States Duration: Feb 28 2016 → Mar 2 2016

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	9783
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2016: Physics of Medical Imaging
Country/Territory	United States
City	San Diego
Period	02/28/16 → 03/2/16

Keywords

X-ray phase contrast
in vivo
propagation based
small animal lung imaging

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10.1117/12.2217267

Cite this

Garson, A. B., Gunsten, S., Vasireddi, S., Brody, S., & Anastasio, M. A. (2016). In vivo small animal lung speckle imaging with a benchtop in-line XPC system. In D. Kontos, J. Y. Lo, & T. G. Flohr (Eds.), Medical Imaging 2016: Physics of Medical Imaging [97834Z] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9783). SPIE. https://doi.org/10.1117/12.2217267

@inproceedings{1a9edd897dce452bb80291b10485a8c9,

title = "In vivo small animal lung speckle imaging with a benchtop in-line XPC system",

abstract = "X-ray phase-contrast (XPC) images of mouse lungs were acquired in vivo with a benchtop XPC system employing a conventional microfocus source. A strong speckled intensity pattern was present in lung regions of the XPC radiographs, previously only observed in synchroton experiments and in situ benchtop studies. We showed how the texture characteristics of the speckle is influenced by the amount of air present in the lungs at different points in the breathing cycle.",

keywords = "X-ray phase contrast, in vivo, propagation based, small animal lung imaging",

author = "Garson, {A. B.} and S. Gunsten and S. Vasireddi and S. Brody and Anastasio, {M. A.}",

note = "Funding Information: This work was supported in part by NSF award CBET1263988. Publisher Copyright: {\textcopyright} 2016 SPIE.; null ; Conference date: 28-02-2016 Through 02-03-2016",

year = "2016",

doi = "10.1117/12.2217267",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Despina Kontos and Lo, {Joseph Y.} and Flohr, {Thomas G.}",

booktitle = "Medical Imaging 2016",

}

Garson, AB, Gunsten, S, Vasireddi, S, Brody, S & Anastasio, MA 2016, In vivo small animal lung speckle imaging with a benchtop in-line XPC system. in D Kontos, JY Lo & TG Flohr (eds), Medical Imaging 2016: Physics of Medical Imaging., 97834Z, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 9783, SPIE, Medical Imaging 2016: Physics of Medical Imaging, San Diego, United States, 02/28/16. https://doi.org/10.1117/12.2217267

In vivo small animal lung speckle imaging with a benchtop in-line XPC system. / Garson, A. B.; Gunsten, S.; Vasireddi, S. et al.

Medical Imaging 2016: Physics of Medical Imaging. ed. / Despina Kontos; Joseph Y. Lo; Thomas G. Flohr. SPIE, 2016. 97834Z (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9783).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - In vivo small animal lung speckle imaging with a benchtop in-line XPC system

AU - Garson, A. B.

AU - Gunsten, S.

AU - Vasireddi, S.

AU - Brody, S.

AU - Anastasio, M. A.

PY - 2016

Y1 - 2016

N2 - X-ray phase-contrast (XPC) images of mouse lungs were acquired in vivo with a benchtop XPC system employing a conventional microfocus source. A strong speckled intensity pattern was present in lung regions of the XPC radiographs, previously only observed in synchroton experiments and in situ benchtop studies. We showed how the texture characteristics of the speckle is influenced by the amount of air present in the lungs at different points in the breathing cycle.

AB - X-ray phase-contrast (XPC) images of mouse lungs were acquired in vivo with a benchtop XPC system employing a conventional microfocus source. A strong speckled intensity pattern was present in lung regions of the XPC radiographs, previously only observed in synchroton experiments and in situ benchtop studies. We showed how the texture characteristics of the speckle is influenced by the amount of air present in the lungs at different points in the breathing cycle.

KW - X-ray phase contrast

KW - in vivo

KW - propagation based

KW - small animal lung imaging

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U2 - 10.1117/12.2217267

DO - 10.1117/12.2217267

M3 - Conference contribution

AN - SCOPUS:84978858591

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Medical Imaging 2016

A2 - Kontos, Despina

A2 - Lo, Joseph Y.

A2 - Flohr, Thomas G.

PB - SPIE

Y2 - 28 February 2016 through 2 March 2016

ER -

In vivo small animal lung speckle imaging with a benchtop in-line XPC system

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