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In vivo real-time imaging reveals megalin as the aminoglycoside gentamicin transporter into cochlea whose inhibition is otoprotective
Jinkyung Kim
, Anthony J. Ricci
Department of Otolaryngology
DBBS - Molecular Cell Biology
Center of Regenerative Medicine
DBBS - Neurosciences
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
DBBS - Biochemistry, Biophysics, and Structural Biology
Research output
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Contribution to journal
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Article
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peer-review
30
Scopus citations
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Dive into the research topics of 'In vivo real-time imaging reveals megalin as the aminoglycoside gentamicin transporter into cochlea whose inhibition is otoprotective'. Together they form a unique fingerprint.
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Keyphrases
Cochlea
100%
Aminoglycosides
100%
Gentamicin
100%
Real-time Imaging
100%
Megalin
100%
Hair Cell
62%
Stria Vascularis
25%
Cilastatin
25%
Knock-in Mouse Model
12%
Sensory Hair Cells
12%
Time Tracking
12%
Hearing Impairment
12%
Antibiotics
12%
Ototoxicity
12%
New Drug Targets
12%
Deafness
12%
Blockage
12%
Texas
12%
Cochleostomy
12%
Cell Degeneration
12%
In Vivo Tracking
12%
Irreversible Loss
12%
Time-lapse
12%
Chemo-mechanical
12%
Mechanotransducer Channel
12%
Transmembrane Channel-like Protein
12%
Neuroscience
In Vivo
100%
Aminoglycoside
100%
Gentamicin
100%
Megalin
100%
Cilastatin
25%
Cochlea
12%
Sensation of Hearing
12%
Synapsin I
12%
Cell Degeneration
12%