In vivo evaluation of a porous, elastic, biodegradable patch for reconstructive cardiac procedures

  • K. L. Fujimoto
  • , J. Guan
  • , H. Oshima
  • , T. Sakai
  • , W. R. Wagner

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The reconstruction of the right ventricular outflow tract (RVOT) of adult rats, the comparison of the tissue response to the poly(ester urethane) urea (PU) patch, and a control patch comprised of expanded poly(tetrafluoroethylene) (ePTFE) were investigated. PU based on poly(caprolactone) butyl diisocyanate and putrescine was synthesized by thermally induced phase separation. Frozen tissue was serially cryosectioned and processed with hematoxylin and eosin. It was found that a biodegradable, elastic PU patch was able to reconstruct the RVOT in a rat model, and showed in vivo behavior.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages507
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
Country/TerritoryAustralia
CitySydney
Period05/17/0405/21/04

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