In vitro synthesis of osteoinductive extracellular matrix for bone tissue engineering

N. Datta, H. L. Holtorf, J. A. Jansen, A. G. Mikos

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The effect of extracellular matrix (ECM) deposited on the differentiation of freshly seeded marrow stromal cells (MSC) was investigated by osteoblastic cells. The calcium was deposited at a greater rate by cells on decellularized scaffolds. The relative osteopontin levels were observed in the retively high ECM deposition exhibited by Ti/ECM/MSC constructs in OS. The results show that the MSC grown on a decellurized scaffold with a preexisting ECM exhibit greater calcium deposition.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages1016
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
Country/TerritoryAustralia
CitySydney
Period05/17/0405/21/04

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