Abstract
When inoculated with sporozoites of Plasmodium berghei, a line of hepatoma cells (HepG2-A16) derived from human liver supports the complete asexual developmental cycle of exoerythrocytic stage. Parasites were shown to resemble parasites in vivo in hepatocytes. Subinoculation of merozoites into mice induced a red blood cell infection.
| Original language | English |
|---|---|
| Pages (from-to) | 682-684 |
| Number of pages | 3 |
| Journal | American Journal of Tropical Medicine and Hygiene |
| Volume | 32 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jan 1 1983 |
| Externally published | Yes |
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Cite this
Hollingdale, M. R., Leland, P., & Schwartz, A. L. (1983). In vitro cultivation of the exoerythrocytic stage of Plasmodium berghei in a hepatoma cell line. American Journal of Tropical Medicine and Hygiene, 32(4), 682-684. https://doi.org/10.4269/ajtmh.1983.32.682