In vitro and in vivo studies of AT-1362, a newly synthesized and orally active inhibitor of thrombin

Keyphrases

• Thrombin 100%
• Orally Active 100%
• Bleeding Time 100%
• Argatroban 100%
• Thrombus Formation 66%
• Vehicle Groups 66%
• Oral Administration 33%
• Inhibition Rate 33%
• Potent Inhibitor 33%
• Selective Inhibitor 33%
• Rat Model 33%
• Transection 33%
• Venous Thrombosis 33%
• Thrombotic 33%
• Competitive Inhibitor 33%
• Activated Partial Thromboplastin Time (aPTT) 33%
• Vessel Patency 33%
• Antithrombotic Agents 33%
• Antithrombotic Effect 33%
• Carotid Artery Thrombosis 33%
• Stasis 33%
• Thrombosis Model 33%
• Iron(III) Chloride 33%
• Rat Tail 33%
• ID50 33%
• Endothelial Disruption 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Bleeding 100%
• Thrombin 100%
• Argatroban 100%
• Anticoagulant Agent 66%
• Thrombus 66%
• Thromboplastin 33%
• Thrombosis 33%
• Rat Model 33%
• Competitive Inhibitor 33%
• Vein Thrombosis 33%
• Carotid Artery Thrombosis 33%