In vitro and in vivo evaluation of ⁶⁴Cu-labeled DOTA-linker-bombesin(7-14) analogues containing different amino acid linker moieties

Keyphrases

• Amino Acids 100%
• Linker 100%
• Bombesin 100%
• In Vivo Evaluation 100%
• Gastrin-releasing Peptide Receptor (GRPr) 57%
• Bombesin-like Peptides 42%
• Bombesin Analogues 42%
• Tumor 28%
• Positron Emission Tomography 28%
• Tissue Uptake 28%
• Glutamic Acid 28%
• Glycine 14%
• Prostate Cancer 14%
• Tumor Subtype 14%
• IC50 Value 14%
• In Vitro Assay 14%
• Prostate Tumor 14%
• Tumor-specific 14%
• Clinical Translation 14%
• Imaging Characteristics 14%
• Positron-emitting Radionuclide 14%
• Copper-64 (64Cu) 14%
• 1,4,7,10-tetraazacyclododecane 14%
• Tumor Uptake 14%
• Positron Emitters 14%
• Radiolabeled Peptides 14%
• Chelates 14%
• Gamma-emitting Radionuclides 14%
• Low Background 14%
• Non-target 14%
• Specific Uptake 14%
• PC-3 Cells 14%
• DOTA Chelator 14%
• Amino Acid Combination 14%
• Aliphatic Linkers 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Tetraxetan 100%
• Amino Acid 100%
• Copper 64 100%
• Bombesin 100%
• Gastrin Releasing Peptide Receptor 57%
• Neoplasm 28%
• Glutamic Acid 28%
• Prostate Cancer 14%
• Prostate Tumor 14%
• Serine 14%
• IC50 14%
• Chelating Agent 14%
• Radioisotope 14%