TY - JOUR
T1 - Impulsivity in adolescent bipolar disorder
AU - Gilbert, Kirsten E.
AU - Kalmar, Jessica H.
AU - Womer, Fay Y.
AU - Markovich, Philip J.
AU - Pittman, Brian
AU - Nolen-Hoeksema, Susan
AU - Blumberg, Hilary P.
N1 - Funding Information:
We wish to thank Kathleen Colonese, Susan Quatrano and Allison McDonough for their work with the adolescents and organisation of the data, and the adolescents and their families for their participation. Funding for this study was provided by the National Institute of Health grants RC1MH088366 (H. P. B.) and R01MH69747 (H. P. B.), UL1DE19586, the Roadmap for Medical Research/Common Fund and RL1DA024856 (H.P.B., J. H. K. and S. N.-H.), T32MH14276 (J. H. K.), the National Alliance for Research in Schizophrenia and Depression (H. P. B. and J. H. K.), the Attias Family Foundation (H. P. B.), Marcia Simon Kaplan (J. H. K.), Women’s Health Research at Yale (H. P. B.) and the Klingenstein Foundation (J. H. K.). These funding sources had no further role in study design; in the collection, analysis and interpretation of data; in the writing of the report and in the decision to submit the paper for publication. All authors declare that they have no conflict of interest.
PY - 2011/4
Y1 - 2011/4
N2 - Gilbert KE, Kalmar JH, Womer FY, Markovich PJ, Pittman B, Nolen-Hoeksema S, Blumberg HP. Impulsivity in adolescent bipolar disorder. Objective: Increased impulsivity has been shown to be a trait feature of adults with bipolar disorder (BD), yet impulsivity has received little study in adolescents with BD. Thus, it is unknown whether it is a trait feature that is present early in the course of the disorder. We tested the hypotheses that self-reported impulsiveness is increased in adolescents with BD, and that it is present during euthymia, supporting impulsiveness as an early trait feature of the disorder. Methods: Impulsiveness was assessed in 23 adolescents with BD and 23 healthy comparison (HC) adolescents using the self-report measure of impulsivity, the Barratt Impulsiveness Scale (BIS), comprised by attentional, motor and non-planning subscale scores. Effects of subscale scores and associations of scores with mood state and course features were explored. Results: Total and subscale BIS scores were significantly higher in adolescents with BD than HC adolescents. Total, attentional and motor subscale BIS scores were also significantly higher in the subset of adolescents with BD who were euthymic, compared to HC adolescents. Adolescents with BD with rapid-cycling and chronic mood symptoms had significantly higher total and motor subscale BIS scores than adolescents with BD without these course features. Conclusion: These results suggest increased self-reported impulsiveness is a trait feature of adolescents with BD. Elevated impulsivity may be especially prominent in adolescents with rapid-cycling and chronic symptoms.
AB - Gilbert KE, Kalmar JH, Womer FY, Markovich PJ, Pittman B, Nolen-Hoeksema S, Blumberg HP. Impulsivity in adolescent bipolar disorder. Objective: Increased impulsivity has been shown to be a trait feature of adults with bipolar disorder (BD), yet impulsivity has received little study in adolescents with BD. Thus, it is unknown whether it is a trait feature that is present early in the course of the disorder. We tested the hypotheses that self-reported impulsiveness is increased in adolescents with BD, and that it is present during euthymia, supporting impulsiveness as an early trait feature of the disorder. Methods: Impulsiveness was assessed in 23 adolescents with BD and 23 healthy comparison (HC) adolescents using the self-report measure of impulsivity, the Barratt Impulsiveness Scale (BIS), comprised by attentional, motor and non-planning subscale scores. Effects of subscale scores and associations of scores with mood state and course features were explored. Results: Total and subscale BIS scores were significantly higher in adolescents with BD than HC adolescents. Total, attentional and motor subscale BIS scores were also significantly higher in the subset of adolescents with BD who were euthymic, compared to HC adolescents. Adolescents with BD with rapid-cycling and chronic mood symptoms had significantly higher total and motor subscale BIS scores than adolescents with BD without these course features. Conclusion: These results suggest increased self-reported impulsiveness is a trait feature of adolescents with BD. Elevated impulsivity may be especially prominent in adolescents with rapid-cycling and chronic symptoms.
KW - adolescents
KW - bipolar disorder
KW - impulsivity
UR - http://www.scopus.com/inward/record.url?scp=79952270866&partnerID=8YFLogxK
U2 - 10.1111/j.1601-5215.2011.00522.x
DO - 10.1111/j.1601-5215.2011.00522.x
M3 - Article
C2 - 21483649
AN - SCOPUS:79952270866
SN - 0924-2708
VL - 23
SP - 57
EP - 61
JO - Acta Neuropsychiatrica
JF - Acta Neuropsychiatrica
IS - 2
ER -