Improved islet yields from pancreas preserved in perflurocarbon is via inhibition of apoptosis mediated by mitochondrial pathway

Keyphrases

• Pancreas 100%
• Apoptosis Inhibition 100%
• Mitochondrial Pathway 100%
• Islet Yield 100%
• Islet 80%
• Perfluorocarbon 80%
• Apoptotic Genes 60%
• Apoptosis 40%
• Hypoxia 40%
• University of Wisconsin Solution 40%
• Treatment Options 20%
• Survivin 20%
• Decreased Expression 20%
• Islet Transplantation 20%
• Fold Increase 20%
• Caspase-3 20%
• Anti-apoptotic 20%
• Caspase Activation 20%
• Caspase 20%
• Pro-apoptotic 20%
• Human Pancreas 20%
• Caspase-8 20%
• Inhibitor of Apoptosis Proteins 20%
• Caspase-9 20%
• Gene Array Analysis 20%
• Varying Condition 20%
• Activated Caspases 20%
• Redox Potential 20%
• Type 1 Diabetic Patient 20%
• Mitochondria-dependent 20%
• Caspase-2 20%
• Two-layer Approach 20%
• Islet Isolation 20%

Biochemistry, Genetics and Molecular Biology

• Programmed Cell Death 100%
• Viaspan 66%
• Caspase 66%
• Upregulation 33%
• Downregulation 33%
• Survivin 33%
• Mitochondrion 33%
• Caspase 3 33%
• DNA Microarray 33%
• Caspase 8 33%
• Inhibitor of Apoptosis 33%
• Caspase-9 33%
• Oxidation Reduction Potential 33%
• Caspase 2 33%