Improved Cardiovascular Disease Outcomes in Older Adults

Daniel E. Forman, Karen Alexander, Ralph G. Brindis, Anne B. Curtis, Mathew Maurer, Michael W. Rich, Laurence Sperling, Nanette K. Wenger

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

Longevity is increasing and the population of older adults is growing. The biology of aging is conducive to cardiovascular disease (CVD), such that prevalence of coronary artery disease, heart failure, valvular heart disease, arrhythmia and other disorders are increasing as more adults survive into old age. Furthermore, CVD in older adults is distinctive, with management issues predictably complicated by multimorbidity, polypharmacy, frailty and other complexities of care that increase management risks (e.g., bleeding, falls, and rehospitalization) and uncertainty of outcomes. In this review, state-of-the-art advances in heart failure, acute coronary syndromes, transcatheter aortic valve replacement, atrial fibrillation, amyloidosis, and CVD prevention are discussed. Conceptual benefits of treatments are considered in relation to the challenges and ambiguities inherent in their application to older patients.

Original languageEnglish
Article number112
JournalF1000Research
Volume5
DOIs
StatePublished - Jan 1 2016

Fingerprint Dive into the research topics of 'Improved Cardiovascular Disease Outcomes in Older Adults'. Together they form a unique fingerprint.

  • Cite this

    Forman, D. E., Alexander, K., Brindis, R. G., Curtis, A. B., Maurer, M., Rich, M. W., Sperling, L., & Wenger, N. K. (2016). Improved Cardiovascular Disease Outcomes in Older Adults. F1000Research, 5, [112]. https://doi.org/10.12688/f1000research.7088.1