Implantable synthetic organoid matrices for intestinal regeneration

Jeffrey W. Brown; Jason C. Mills

doi:10.1038/ncb3635

Implantable synthetic organoid matrices for intestinal regeneration

Jeffrey W. Brown
, Jason C. Mills

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Organoids are a powerful tool to study both physiological and disease processes. A completely synthetic matrix assembled from exchangeable modular parts has been developed and not only supports proliferation of human intestinal organoids derived from pluripotent embryonic stem cells, but also augments subsequent ad vivo implantation into injured murine colon.

Original language	English
Pages (from-to)	1307-1308
Number of pages	2
Journal	Nature Cell Biology
Volume	19
Issue number	11
DOIs	https://doi.org/10.1038/ncb3635
State	Published - Nov 1 2017

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title = "Implantable synthetic organoid matrices for intestinal regeneration",

abstract = "Organoids are a powerful tool to study both physiological and disease processes. A completely synthetic matrix assembled from exchangeable modular parts has been developed and not only supports proliferation of human intestinal organoids derived from pluripotent embryonic stem cells, but also augments subsequent ad vivo implantation into injured murine colon.",

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AU - Mills, Jason C.

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AB - Organoids are a powerful tool to study both physiological and disease processes. A completely synthetic matrix assembled from exchangeable modular parts has been developed and not only supports proliferation of human intestinal organoids derived from pluripotent embryonic stem cells, but also augments subsequent ad vivo implantation into injured murine colon.

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U2 - 10.1038/ncb3635

DO - 10.1038/ncb3635

M3 - Review article

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SP - 1307

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JO - Nature Cell Biology

JF - Nature Cell Biology

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Implantable synthetic organoid matrices for intestinal regeneration

Abstract

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