Impairment of the collagenase-3 endocytotic receptor system in cells from patients with osteoarthritis

Keyphrases

• Osteoarthritis 100%
• Receptor Systems 100%
• Collagenase 3 100%
• Osteoarthritis Chondrocyte 33%
• Receptor-mediated 16%
• Low-density Lipoprotein Receptor-related protein-1 (LRP1) 16%
• Cartilage Matrix 16%
• Recombinant 8%
• Family Members 8%
• Primary Culture 8%
• Quantitative PCR 8%
• Enzyme-linked Immunosorbent Assay (ELISA) 8%
• Low-density Lipoprotein Receptor 8%
• Receptor-interacting Protein Kinase 1 (RIPK1) 8%
• Knee Osteoarthritis 8%
• Matrix Metalloproteinase 13 (MMP13) 8%
• Intracellular Degradation 8%
• Human Chondrocytes 8%
• Control Specimen 8%
• Iodinated 8%
• Fibroblast Cells 8%
• Aggrecan 8%
• Autopsy 8%
• Pericellular 8%
• Novel Therapeutic Targets 8%
• Matrix Degradation 8%
• Chondrocyte Phenotype 8%
• Osteoblastic Cells 8%
• Joint Replacement Surgery 8%
• Collagen II 8%
• Synoviocytes 8%
• Cell Surface Binding 8%
• 3′ End Processing 8%
• Local Degradation 8%
• LRP1 Receptor 8%
• Human Synoviocytes 8%

Immunology and Microbiology

• Osteoarthritis 100%
• Chondrocyte 100%
• Internalization 50%
• LRP1 50%
• Cartilage Matrix 33%
• Synoviocyte 33%
• Knee 16%
• Iodine-125 16%
• Cell Surface 16%
• Primary Culture 16%
• Aggrecan 16%
• Low Density Lipoprotein Receptor Related Protein 16%
• Reverse Transcription Polymerase Chain Reaction 16%
• Therapeutic Target 16%

Biochemistry, Genetics and Molecular Biology

• Collagenase 100%
• Chondrocyte 50%
• LRP1 25%
• Internalization 25%
• Enzyme 16%
• Iodine-125 8%
• Matrix Metalloproteinase 8%
• Primary Culture 8%
• LDL Receptor 8%
• Lipoprotein Receptor-Related Protein 8%
• Aggrecan 8%
• Reverse Transcription Polymerase Chain Reaction 8%