Impact of Intravenous Iron Supplementation Before Coronary Artery Bypass Grafting

Mehmet Cahit Saricaoglu, Onat Bermede

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Current studies, link preoperative anemia to problematic perioperative period, including higher rates of red blood cell transfusion need, longer hospital stay time, higher rates of acute kidney injury, myocardial infarction, stroke and increased mortality. The aim of this retrospective study was to analyze the impact of preoperative intravenous supplementation of iron on postoperative adverse events in patients undergoing elective coronary artery bypass grafting (CABG). Methods: This single center, retrospective, observational study investigated patients who underwent CABG surgery between 2016-2019. The patients, who were above 18 years old, had iron deficiency anemia (IDA) and underwent elective isolated CABG surgery were included in this study. Results: Population of this study was consisted of 84 (51.2%) men and the median age of the whole population was 66 (39-80) years old. Preoperative iron supplementation was statistically associated with shorter length of hospital stay and lower in-hospital mortality. More patients in IDA group without iron supplementation needed red blood cell transfusion postoperatively. Preoperative iron supplementation was independently associated with lower risk for in-hospital mortality in patients with IDA who underwent isolated CABG. In addition, 1 unit decrease in preoperative hemoglobin level was found to be related with a 1.8-fold higher risk of mortality. Conclusion: This study showed that preoperative intravenous infusion of iron is related with a shorter length of hospital stay and reduced perioperative red blood cell transfusion requirement. In-hospital mortality was significantly lower in pretreated patients with iron.

Original languageEnglish
Pages (from-to)357-362
Number of pages6
JournalAnestezi Dergisi
Volume31
Issue number4
DOIs
StatePublished - 2023

Keywords

  • anemia
  • coronary artery bypass grafting
  • Iron deficiency
  • iron supplementation

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