Impact of insertion site on complications in central venous access devices

Sara A. Mansfield, Jessica Staszak, Andrew J. Murphy, Lindsay Talbot, Abdelhafeez Abdelhafeez, Hasmukh Prajapati, Robert Gold, Vinod Maller, Kimberly Proctor, Andrew M. Davidoff, Regan F. Williams

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Purpose: There is still debate over the safest route for the placement of long-term central venous access devices. The aim of this study was to review a large, single-institution experience to determine the impact of access location on peri-operative complications. Methods: The records of patients undergoing subcutaneous port (SQP) and tunneled catheter insertion over a seven-year period were reviewed. Vein cannulated (subclavian (SCV) versus internal jugular (IJ) vein), and 30-day complications were assessed. Surgical complications included pneumothorax, hemothorax, infections, arrhythmia or malpositioning requiring intervention. Results: A total of 1,309 patients were included (618 SQP, 691 tunneled catheters). The location for insertion was SCV (909, 69.4%) and IJ (400, 30.6%). There were 69 complications (5.2%) (41, 4.5% SCV, 28, 7.0% IJV) including: malpositioning/malfunctioning (SCV 13, 1.4% and IJV 14, 3.0%), pneumothorax (SCV 4, 0.4% and IJV 1, 0.3%), hemothorax (SCV 0 and IJV 1, 0.3%), arrhythmia (SCV 1, 0.1%, and IJV 0), and infection within 30 days of placement (SCV 20, 2.2% and IJ 11, 2.8%). The complication rates were not significantly different based on site (p = 0.080). Conclusion: There was no significant difference in complication rates when using the subclavian versus the internal jugular vein as the site for long-term central venous access. Level of evidence: III, retrospective comparative study.

Original languageEnglish
Article number118
JournalPediatric Surgery International
Issue number1
StatePublished - Dec 2023


  • Access site
  • Central venous access devices
  • Internal jugular vein
  • Pediatric oncology
  • Subclavian vein


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