TY - JOUR
T1 - Impact of chorionicity on risk and timing of intrauterine fetal demise in twin pregnancies
AU - McPherson, Jessica A.
AU - Odibo, Anthony O.
AU - Shanks, Anthony L.
AU - Roehl, Kimberly A.
AU - MacOnes, George A.
AU - Cahill, Alison G.
PY - 2012/9
Y1 - 2012/9
N2 - Objective: We sought to estimate the association between chorionicity and intrauterine fetal demise (IUFD) of one or both fetuses in twin pregnancies. Study Design: In a retrospective cohort of twins undergoing anatomic survey, risk of IUFD in monochorionic and dichorionic twins was compared. The primary outcome was IUFD of one or both fetuses; secondary outcomes included nonanomalous fetal deaths. Results: Of 2161 twin pregnancies meeting inclusion criteria, 86 had at least 1 IUFD and 32 experienced a double fetal loss. Monochorionic pregnancies had an increased risk of a single demise (adjusted odds ratio, 1.69; 95% confidence interval, 1.04-2.75) and a double demise (adjusted odds ratio, 2.11; 95% confidence interval, 1.02-4.37). Of all double demises, 70% occurred <24 weeks. Conclusion: Monochorionic twins carry an increased risk of fetal death compared to dichorionic twins. Double demise occurs primarily <24 weeks, regardless of chorionicity.
AB - Objective: We sought to estimate the association between chorionicity and intrauterine fetal demise (IUFD) of one or both fetuses in twin pregnancies. Study Design: In a retrospective cohort of twins undergoing anatomic survey, risk of IUFD in monochorionic and dichorionic twins was compared. The primary outcome was IUFD of one or both fetuses; secondary outcomes included nonanomalous fetal deaths. Results: Of 2161 twin pregnancies meeting inclusion criteria, 86 had at least 1 IUFD and 32 experienced a double fetal loss. Monochorionic pregnancies had an increased risk of a single demise (adjusted odds ratio, 1.69; 95% confidence interval, 1.04-2.75) and a double demise (adjusted odds ratio, 2.11; 95% confidence interval, 1.02-4.37). Of all double demises, 70% occurred <24 weeks. Conclusion: Monochorionic twins carry an increased risk of fetal death compared to dichorionic twins. Double demise occurs primarily <24 weeks, regardless of chorionicity.
KW - intrauterine fetal demise
KW - multiple gestation
UR - http://www.scopus.com/inward/record.url?scp=84865703304&partnerID=8YFLogxK
U2 - 10.1016/j.ajog.2012.07.031
DO - 10.1016/j.ajog.2012.07.031
M3 - Article
C2 - 22939722
AN - SCOPUS:84865703304
SN - 0002-9378
VL - 207
SP - 190.e1-190.e6
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 3
ER -