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Impact of aging on substrate metabolism by the human heart
Andrew M. Kates
, Pilar Herrero
, Carmen Dence
, Pablo Soto
, Muthayyah Srinivasan
, Deborah G. Delano
, Ali Ehsani
,
Robert J. Gropler
Division of Cardiology
Division of Radiological Sciences
Institute of Clinical and Translational Sciences (ICTS)
Siteman Cancer Center
Division of Veterans Affairs
Department of Radiology
Research output
:
Contribution to journal
›
Article
›
peer-review
170
Scopus citations
Overview
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Keyphrases
11C-acetate
16%
15O-water
16%
Absolute Rates
16%
Aging
100%
Clinical Significance
16%
Experimental Animals
16%
Fasted State
16%
Fatty Acid Metabolism
16%
Fatty Acid Oxidation
16%
Fatty Acid Utilization
83%
Free Fatty Acids
33%
Glucose Metabolism
16%
Glucose Utilization
66%
Healthy Young
16%
Human Heart
100%
Metabolic Switch
16%
MVO2
100%
Myocardial Blood Flow
33%
Myocardial Oxygen Consumption
16%
Normal Volunteers
16%
Older Subjects
33%
Older Volunteers
16%
Palmitate
16%
Positron Emission Tomography
33%
Relative Contribution
16%
Resting Conditions
16%
Substrate Metabolism
100%
Young Subjects
33%
Biochemistry, Genetics and Molecular Biology
Experimental Animal
25%
Fatty Acid Metabolism
25%
Free Fatty Acids
50%
Glucose Metabolism
25%
Glucose Utilization
100%
Heart Muscle Blood Flow
50%
Heart Muscle Oxygen Consumption
25%
Human Aging
25%
Metabolic Pathway
100%
Normal Human
25%
Palmitic Acid
25%
Positron Emission Tomography
50%
Medicine and Dentistry
Acetic Acid
14%
Carbon 11
42%
Clinical Significance
14%
Fatty Acid
100%
Fatty Acid Metabolism
14%
Glucose Metabolism
14%
Glucose Utilization
57%
Heart Muscle Blood Flow
28%
Heart Muscle Oxygen Consumption
14%
Oxygen 15
14%
Palmitic Acid
14%
Positron Emission Tomography
28%
Volunteer
28%
Immunology and Microbiology
Acetate
14%
Experimental Animal
14%
Fatty Acid
100%
Fatty Acid Metabolism
14%
Glucose Metabolism
14%
Glucose Utilization
57%
Heart Muscle Blood Flow
28%
Heart Muscle Oxygen Consumption
14%
Normal Human
14%
Positron Emission Tomography
28%
Pharmacology, Toxicology and Pharmaceutical Science
Carbon 11
37%
Experimental Animal
12%
Fatty Acid
100%
Normal Human
12%
Oxygen 15
12%
Palmitic Acid
12%
Food Science
Free Fatty Acids
100%