Immunohistochemical markers of prognostic value in surgical pathology

C. R. Taylor, R. J. Cote

Research output: Contribution to journalReview article

24 Scopus citations

Abstract

Immunohistochemical methods have enjoyed rapid growth in application and utility since their initial adaptation to paraffin sections 20 years ago. Initial applications were directed primarily to the identification of cell and tumor sub-types (lineage related markers). More recently immunohistochemical markers have been described that show great promise in determining tumor prognosis, at a very early stage of tumor development, independent of stage and grade. This review surveys the recent use of immunohistochemistry in prognosis, and offers some speculation as to areas of future promise.

Original languageEnglish
Pages (from-to)1039-1055
Number of pages17
JournalHistology and Histopathology
Volume12
Issue number4
StatePublished - Oct 8 1997
Externally publishedYes

Keywords

  • Immunohistochemistry
  • Micrometastases
  • Oncogenes
  • Prognostic markers
  • Proliferation markers
  • Tumor suppressor genes

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