A case of non-Hodgkin's lymphoma of T-cell type occurring in a renal transplant recipient is described. This lymphoma was classified as large cell, immunoblastic type and presented as a mediastinal mass, although it was demonstrated to be disseminated at autopsy two weeks later. Lymphoma cells expressed the immunologic profile of a mature, activated cytotoxic/suppressor T-lymphocyte. T-cell receptor gene rearrangement and karyotypic studies confirmed a clonal T-cell genotype. Molecular studies failed to demonstrate any association with Epstein-Barr virus or human T-cell lymphotropic virus type I or type II. Pathogenesis of lymphomas in this clinical setting is discussed.

Original languageEnglish
Pages (from-to)280-285
Number of pages6
JournalAmerican journal of clinical pathology
Issue number2
StatePublished - 1990


  • T-cell lymphoma
  • immunoblastic lymphoma
  • renal transplant


Dive into the research topics of 'Immunoblastic lymphoma of T-cell type in a chronically immunosuppressed renal transplant recipient'. Together they form a unique fingerprint.

Cite this