IMMUNISATION WITH A POLYVALENT PNEUMOCOCCAL VACCINE. Reduction of Adult Respiratory Mortality in a New Guinea Highlands Community

I. D. Riley; M. Andrews; R. Howard; P. I. Tarr; M. Pfeiffer; P. Challands; G. Jennison; R. M. Douglas

doi:10.1016/S0140-6736(77)92552-1

IMMUNISATION WITH A POLYVALENT PNEUMOCOCCAL VACCINE. Reduction of Adult Respiratory Mortality in a New Guinea Highlands Community

I. D. Riley
, M. Andrews
, R. Howard
, P. I. Tarr
, M. Pfeiffer
, P. Challands
, G. Jennison
, R. M. Douglas

Research output: Contribution to journal › Article › peer-review

145 Scopus citations

Abstract

A double-blind controlled trial of a 14-valent pneumococcal polysaccharide vaccine was carried out in 11 958 adults at Tari in the Papua New Guinea Highlands. Pneumococcal infection, confirmed by blood-culture and lung aspirate, was less in the vaccinated group by 84%. Mortality from pneumonia was less by 44%.

Original language	English
Pages (from-to)	1338-1341
Number of pages	4
Journal	The Lancet
Volume	309
Issue number	8026
DOIs	https://doi.org/10.1016/S0140-6736(77)92552-1
State	Published - Jun 25 1977

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@article{0027c5cfc2304a128dcd32e4e9f9fbe3,

title = "IMMUNISATION WITH A POLYVALENT PNEUMOCOCCAL VACCINE. Reduction of Adult Respiratory Mortality in a New Guinea Highlands Community",

abstract = "A double-blind controlled trial of a 14-valent pneumococcal polysaccharide vaccine was carried out in 11 958 adults at Tari in the Papua New Guinea Highlands. Pneumococcal infection, confirmed by blood-culture and lung aspirate, was less in the vaccinated group by 84\%. Mortality from pneumonia was less by 44\%.",

author = "Riley, \{I. D.\} and M. Andrews and R. Howard and Tarr, \{P. I.\} and M. Pfeiffer and P. Challands and G. Jennison and Douglas, \{R. M.\}",

note = "Funding Information: This work is supported by the Medical Research Council, London, and the World Health Organisation. We thank Dr R. S. Bray for Funding Information: The trial was supported by the Department of Public Health, Papua New Guinea, and by a grant from Merck, Sharp and Dohme Limited,",

year = "1977",

month = jun,

day = "25",

doi = "10.1016/S0140-6736(77)92552-1",

language = "English",

volume = "309",

pages = "1338--1341",

journal = "The Lancet",

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T1 - IMMUNISATION WITH A POLYVALENT PNEUMOCOCCAL VACCINE. Reduction of Adult Respiratory Mortality in a New Guinea Highlands Community

AU - Riley, I. D.

AU - Andrews, M.

AU - Howard, R.

AU - Tarr, P. I.

AU - Pfeiffer, M.

AU - Challands, P.

AU - Jennison, G.

AU - Douglas, R. M.

N1 - Funding Information: This work is supported by the Medical Research Council, London, and the World Health Organisation. We thank Dr R. S. Bray for Funding Information: The trial was supported by the Department of Public Health, Papua New Guinea, and by a grant from Merck, Sharp and Dohme Limited,

PY - 1977/6/25

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N2 - A double-blind controlled trial of a 14-valent pneumococcal polysaccharide vaccine was carried out in 11 958 adults at Tari in the Papua New Guinea Highlands. Pneumococcal infection, confirmed by blood-culture and lung aspirate, was less in the vaccinated group by 84%. Mortality from pneumonia was less by 44%.

AB - A double-blind controlled trial of a 14-valent pneumococcal polysaccharide vaccine was carried out in 11 958 adults at Tari in the Papua New Guinea Highlands. Pneumococcal infection, confirmed by blood-culture and lung aspirate, was less in the vaccinated group by 84%. Mortality from pneumonia was less by 44%.

UR - https://www.scopus.com/pages/publications/0017750198

U2 - 10.1016/S0140-6736(77)92552-1

DO - 10.1016/S0140-6736(77)92552-1

M3 - Article

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AN - SCOPUS:0017750198

SN - 0140-6736

VL - 309

SP - 1338

EP - 1341

JO - The Lancet

JF - The Lancet

IS - 8026

ER -

IMMUNISATION WITH A POLYVALENT PNEUMOCOCCAL VACCINE. Reduction of Adult Respiratory Mortality in a New Guinea Highlands Community

Abstract

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