Immune modules shared by innate lymphoid cells and T cells

Michelle L. Robinette, Marco Colonna

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations

Abstract

In recent years, innate lymphoid cells (ILCs) have emerged as innate correlates to T cells. The similarities between ILCs and T cells indicate that lymphocytes of fundamentally distinct lineages can share core “immune modules” that encompass transcriptional circuitry and effector functions while using nonredundant complementary mechanisms of pattern recognition to enact these functions. We review modules currently recognized to be shared between ILCs and T cells.

Original languageEnglish
Pages (from-to)1243-1251
Number of pages9
JournalJournal of Allergy and Clinical Immunology
Volume138
Issue number5
DOIs
StatePublished - Nov 1 2016

Keywords

  • Innate lymphoid cell
  • T cell
  • adaptive
  • innate
  • lymphocyte

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