Immune cells perturb axons and impair neuronal survival in a mouse model of infantile neuronal ceroid lipofuscinosis

Keyphrases

• Mouse Model 100%
• Axon 100%
• Lymphocytes 100%
• Immune Cells 100%
• Neuronal Survival 100%
• Neuronal Ceroid Lipofuscinosis 100%
• CD8+ T Lymphocytes 66%
• Visual System 66%
• Disease Progression 33%
• Neuroinflammation 33%
• Microglial Activation 33%
• Central Nervous System 33%
• Infiltration 33%
• Neurodegenerative Diseases 33%
• Gene-deficient Mice 33%
• Inflammatory Cells 33%
• Treatment Strategy 33%
• Axonal Transport 33%
• Disease Phenotype 33%
• RAG1 33%
• Acyl Protein Thioesterase 33%
• PPT1 33%
• CLN1 Disease 33%
• Reconstitution Experiments 33%
• Macrophage-like 33%
• Retinotectal System 33%

Medicine and Dentistry

• Immunocompetent Cell 100%
• Infantile Neuronal Ceroid Lipofuscinosis 100%
• Lymphocyte 100%
• Axon 100%
• CD8 Antigen 66%
• T Lymphocyte 66%
• Diseases 66%
• Neuroinflammation 33%
• Microglia 33%
• Macrophage 33%
• Disease Exacerbation 33%
• Inflammatory Cell 33%
• Central Nervous System 33%
• Neurodegenerative Disorder 33%
• Palmitoyl Protein Thioesterase 33%
• Batten Disease 33%
• Axoplasmic Transport 33%