Immune cell heterogeneity in a mouse model of diabetic kidney disease

Haojia Wu; Benjamin D. Humphreys

doi:10.1016/j.kint.2022.09.007

Immune cell heterogeneity in a mouse model of diabetic kidney disease

Research output: Contribution to journal › Comment/debate

Abstract

Typical kidney single-cell RNA-sequencing contains relatively few leukocytes, complicating efforts to understand how immune cells impact kidney disease progression. In this issue, Fu et al. use a flow sorting strategy to generate a very large immune cell single-cell RNA-sequencing atlas in a mouse model of diabetic kidney disease. These findings highlight the importance of leukocyte cell subtypes in diabetic kidney disease.

Original language	English
Pages (from-to)	1215-1216
Number of pages	2
Journal	Kidney International
Volume	102
Issue number	6
DOIs	https://doi.org/10.1016/j.kint.2022.09.007
State	Published - Dec 2022

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10.1016/j.kint.2022.09.007

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title = "Immune cell heterogeneity in a mouse model of diabetic kidney disease",

abstract = "Typical kidney single-cell RNA-sequencing contains relatively few leukocytes, complicating efforts to understand how immune cells impact kidney disease progression. In this issue, Fu et al. use a flow sorting strategy to generate a very large immune cell single-cell RNA-sequencing atlas in a mouse model of diabetic kidney disease. These findings highlight the importance of leukocyte cell subtypes in diabetic kidney disease.",

author = "Haojia Wu and Humphreys, \{Benjamin D.\}",

note = "Publisher Copyright: {\textcopyright} 2022 International Society of Nephrology",

year = "2022",

month = dec,

doi = "10.1016/j.kint.2022.09.007",

language = "English",

volume = "102",

pages = "1215--1216",

journal = "Kidney International",

issn = "0085-2538",

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T1 - Immune cell heterogeneity in a mouse model of diabetic kidney disease

AU - Wu, Haojia

AU - Humphreys, Benjamin D.

PY - 2022/12

Y1 - 2022/12

N2 - Typical kidney single-cell RNA-sequencing contains relatively few leukocytes, complicating efforts to understand how immune cells impact kidney disease progression. In this issue, Fu et al. use a flow sorting strategy to generate a very large immune cell single-cell RNA-sequencing atlas in a mouse model of diabetic kidney disease. These findings highlight the importance of leukocyte cell subtypes in diabetic kidney disease.

AB - Typical kidney single-cell RNA-sequencing contains relatively few leukocytes, complicating efforts to understand how immune cells impact kidney disease progression. In this issue, Fu et al. use a flow sorting strategy to generate a very large immune cell single-cell RNA-sequencing atlas in a mouse model of diabetic kidney disease. These findings highlight the importance of leukocyte cell subtypes in diabetic kidney disease.

UR - https://www.scopus.com/pages/publications/85141535237

U2 - 10.1016/j.kint.2022.09.007

DO - 10.1016/j.kint.2022.09.007

M3 - Comment/debate

C2 - 36411016

AN - SCOPUS:85141535237

SN - 0085-2538

VL - 102

SP - 1215

EP - 1216

JO - Kidney International

JF - Kidney International

IS - 6

ER -

Immune cell heterogeneity in a mouse model of diabetic kidney disease

Abstract

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