Imaging vasculature and lymphatic flow in mice using quantum dots

Byron Ballou, Lauren A. Ernst, Susan Andreko, James A.J. Fitzpatrick, B. Christoffer Lagerholm, Alan S. Waggoner, Marcel P. Bruchez

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

7 Scopus citations

Abstract

Quantum dots are ideal probes for fluorescent imaging of vascular and lymphatic tissues. On injection into appropriate sites, red- and near-infrared-emitting quantum dots provide excellent definition of vasculature, lymphoid organs, and lymph nodes draining both normal tissues and tumors. We detail methods for use with commercially available quantum dots and discuss common difficulties.

Original languageEnglish
Title of host publicationBioluminescence
Subtitle of host publicationMethods and Protocols
PublisherHumana Press Inc.
Pages63-74
Number of pages12
ISBN (Print)9781603273206
DOIs
StatePublished - 2009
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume574
ISSN (Print)1064-3745

Keywords

  • Quantum dots
  • animals
  • circulation
  • in vivo
  • lymph nodes
  • lymphatic vessels
  • sentinel lymph nodes
  • vasculature

Fingerprint Dive into the research topics of 'Imaging vasculature and lymphatic flow in mice using quantum dots'. Together they form a unique fingerprint.

Cite this