Imaging Sigma-1 Receptor (S1R) Expression Using Iodine-124-Labeled 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine ([¹²⁴I]IPAG)

Keyphrases

• Adamantyl 100%
• Athymic nude Mice 5%
• Biodistribution Studies 5%
• Breast Cancer 5%
• Chloramine 5%
• Competitive Inhibition 5%
• Ethanol 5%
• Guanidine 100%
• Haloperidol 17%
• High Affinity 5%
• Human Cancer 5%
• Imaging Studies 5%
• In Vitro Study 5%
• Inhibition Studies 5%
• Iodine-124 100%
• LNCaP 11%
• MCF-7 5%
• MCF-7 Cancer Cell Line 5%
• Micro-positron Emission Tomography 5%
• Non-target Organisms 5%
• Overexpressing 11%
• Positron Emission Tomography 5%
• Quantitative Yield 5%
• Receptor Expression 100%
• Sigma-1 Receptor 100%
• Sigma-1 Receptor Antagonist 5%
• Tracer Dilution Method 11%
• Tributyltin 5%
• Tumor 47%
• Tumor-to-background Ratio 5%

Medicine and Dentistry

• 1 (2 Adamantyl) 3 (4 Iodophenyl)guanidine 100%
• Biodistribution 3%
• Breast Cancer 3%
• Breast Cancer Cell Line 3%
• Cancer 7%
• Competitive Inhibition 3%
• Haloperidol 11%
• High-Performance Liquid Chromatography 3%
• In Vitro 11%
• Intravenous Drug Administration 3%
• Iodine 124 100%
• MCF-7 3%
• Neoplasm 11%
• Oxidizing Agent 3%
• Positron Emission Tomography 7%
• Precursor 3%
• Radioactive Tracer 7%
• Receptor Antagonist 3%
• Receptor Expression 100%
• Sigma 1 Opiate Receptor 100%
• Target Organ 3%
• Tosylchloramide Sodium 3%
• Tributyltin 3%
• Tumor 22%

Pharmacology, Toxicology and Pharmaceutical Science

• 1 (2 Adamantyl) 3 (4 Iodophenyl)guanidine 100%
• 4 (para chlorophenyl) 1 [3 (para fluorobenzoyl)propyl] 4 piperidinol 11%
• Biodistribution 3%
• Breast Cancer 7%
• Chloramine-T 3%
• High Performance Liquid Chromatography 3%
• Iodine 124 100%
• Neoplasm 11%
• Nude Mouse 3%
• Oxidizing Agent 3%
• Receptor Antagonist 3%
• Sigma 1 Opiate Receptor 100%
• Tracer 7%
• Tributyltin 3%