Imaging of tumor hypoxia using 4-nitroimidazole indocyanine green dye-conjugate in BALB/c tumor- bearing female mice

Akram Abuteen; Feifei Zhou; Christopher Dietz; Innus Mohammad; Michael B. Smith; Quing Zhu

Imaging of tumor hypoxia using 4-nitroimidazole indocyanine green dye-conjugate in BALB/c tumor- bearing female mice

Akram Abuteen
, Feifei Zhou
, Christopher Dietz
, Innus Mohammad
, Michael B. Smith
, Quing Zhu

Department of Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

We compared in vivo hypoxia targeting of 4-nitroimidazole-piperazine-indocyanine derivative (6) with imidazole- (5) and 2-nitroimidazole-indocyanine dye-conjugate (4). Results showed 1.5-fold and 2.5-fold intensity ratio between each pair. This is also supported by cell and immunohistochemistry results.

Original language	English
Title of host publication	Optical Tomography and Spectroscopy, OTS 2016
Publisher	Optica Publishing Group (formerly OSA)
Pages	3
Number of pages	1
ISBN (Print)	9781943580101
State	Published - Apr 18 2016
Event	Optical Tomography and Spectroscopy, OTS 2016 - Fort Lauderdale, United States Duration: Apr 25 2016 → Apr 28 2016

Publication series

Name	Optics InfoBase Conference Papers
ISSN (Electronic)	2162-2701

Conference

Conference	Optical Tomography and Spectroscopy, OTS 2016
Country/Territory	United States
City	Fort Lauderdale
Period	04/25/16 → 04/28/16

Cite this

@inproceedings{ad5d221fc379411094fb203dced4d731,

title = "Imaging of tumor hypoxia using 4-nitroimidazole indocyanine green dye-conjugate in BALB/c tumor- bearing female mice",

abstract = "We compared in vivo hypoxia targeting of 4-nitroimidazole-piperazine-indocyanine derivative (6) with imidazole- (5) and 2-nitroimidazole-indocyanine dye-conjugate (4). Results showed 1.5-fold and 2.5-fold intensity ratio between each pair. This is also supported by cell and immunohistochemistry results.",

author = "Akram Abuteen and Feifei Zhou and Christopher Dietz and Innus Mohammad and Smith, \{Michael B.\} and Quing Zhu",

note = "Publisher Copyright: {\textcopyright} OSA 2016.; Optical Tomography and Spectroscopy, OTS 2016 ; Conference date: 25-04-2016 Through 28-04-2016",

year = "2016",

month = apr,

day = "18",

language = "English",

isbn = "9781943580101",

series = "Optics InfoBase Conference Papers",

publisher = "Optica Publishing Group (formerly OSA)",

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booktitle = "Optical Tomography and Spectroscopy, OTS 2016",

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Abuteen, A, Zhou, F, Dietz, C, Mohammad, I, Smith, MB & Zhu, Q 2016, Imaging of tumor hypoxia using 4-nitroimidazole indocyanine green dye-conjugate in BALB/c tumor- bearing female mice. in Optical Tomography and Spectroscopy, OTS 2016. Optics InfoBase Conference Papers, Optica Publishing Group (formerly OSA), pp. 3, Optical Tomography and Spectroscopy, OTS 2016, Fort Lauderdale, United States, 04/25/16.

Imaging of tumor hypoxia using 4-nitroimidazole indocyanine green dye-conjugate in BALB/c tumor- bearing female mice. / Abuteen, Akram; Zhou, Feifei; Dietz, Christopher et al.
Optical Tomography and Spectroscopy, OTS 2016. Optica Publishing Group (formerly OSA), 2016. p. 3 (Optics InfoBase Conference Papers).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Imaging of tumor hypoxia using 4-nitroimidazole indocyanine green dye-conjugate in BALB/c tumor- bearing female mice

AU - Abuteen, Akram

AU - Zhou, Feifei

AU - Dietz, Christopher

AU - Mohammad, Innus

AU - Smith, Michael B.

AU - Zhu, Quing

PY - 2016/4/18

Y1 - 2016/4/18

N2 - We compared in vivo hypoxia targeting of 4-nitroimidazole-piperazine-indocyanine derivative (6) with imidazole- (5) and 2-nitroimidazole-indocyanine dye-conjugate (4). Results showed 1.5-fold and 2.5-fold intensity ratio between each pair. This is also supported by cell and immunohistochemistry results.

AB - We compared in vivo hypoxia targeting of 4-nitroimidazole-piperazine-indocyanine derivative (6) with imidazole- (5) and 2-nitroimidazole-indocyanine dye-conjugate (4). Results showed 1.5-fold and 2.5-fold intensity ratio between each pair. This is also supported by cell and immunohistochemistry results.

UR - https://www.scopus.com/pages/publications/85016758214

M3 - Conference contribution

AN - SCOPUS:85016758214

SN - 9781943580101

T3 - Optics InfoBase Conference Papers

SP - 3

BT - Optical Tomography and Spectroscopy, OTS 2016

PB - Optica Publishing Group (formerly OSA)

T2 - Optical Tomography and Spectroscopy, OTS 2016

Y2 - 25 April 2016 through 28 April 2016

ER -

Imaging of tumor hypoxia using 4-nitroimidazole indocyanine green dye-conjugate in BALB/c tumor- bearing female mice

Abstract

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