Imaging dopamine receptors in the human brain by positron tomography

Henry N. Wagner, H. Donald Burns, Robert E. Dannals, Dean F. Wong, Bengt Langstrom, Timothy Duelfer, J. James Frost, Hayden T. Ravert, Jonathan M. Links, Shelley B. Rosenbloom, Scott E. Lukas, Alfred V. Kramer, Michael J. Kuhar

Research output: Contribution to journalArticlepeer-review

538 Scopus citations


Neurotransmitter receptors may be involved in a number of neuropsy chiatric disease states. The ligand 3-N-[11C]methylspiperone, which preferentially binds to dopamine receptors in vivo, was used to image the receptors by positron emission tomography scanning in baboons and in humans. This technique holds promise for noninvasive clinical studies of dopamine receptors in humans.

Original languageEnglish
Pages (from-to)1264-1266
Number of pages3
Issue number4617
StatePublished - 1983


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