Image-guided percutaneous ablation of hepatic malignancies

Gretchen Foltz

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


The liver is a common site of primary and secondary malignancies, often resulting in significant morbidity and mortality. Evaluating these patients in a multidisciplinary setting allows for optimal utilization of all oncologic therapies including surgery, radiation, systemic chemotherapy, transarterial therapies, and ablation. While surgical intervention often provides the best outcomes when treating most hepatic tumors, many patients are not surgical candidates due to extensive tumor burden, underlying liver disease, or other comorbid conditions. The evolution of imaging and ablation devices has allowed for the increased utilization of percutaneous ablation as definitive and palliative treatment of primary and metastatic hepatic malignancies. Ablation induces tumor necrosis by injection of chemicals (chemical ablation) or temperature modification (thermal ablation). The goal of this review is to provide an overview of different ablation techniques commonly used for hepatic malignancies, discuss the oncologic outcomes of these interventions, and outline the current indications, contraindications, and reported complications of these therapies.

Original languageEnglish
Pages (from-to)180-186
Number of pages7
JournalSeminars in Interventional Radiology
Issue number2
StatePublished - Jun 2014


  • hepatic metastases
  • hepatocellular carcinoma
  • interventional radiology
  • percutaneous ablation


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