Abstract
A nonimmunocompromised patient developed life-threatening soft tissue infection with Trichosporon asahii, Fusarium, and Saksenaea that progressed despite maximum antifungal therapies and aggressive debridement. Interleukin-7 immunotherapy resulted in clinical improvement, fungal clearance, reversal of lymphopenia, and improved T-cell function. Immunoadjuvant therapies to boost host immunity may be efficacious in life-threatening fungal infections.
Original language | English |
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Article number | ofab256 |
Journal | Open Forum Infectious Diseases |
Volume | 8 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2021 |
Keywords
- Trichosporon
- fungal infection
- immunotherapy
- interleukin-7
- wound infection