@article{d655376f44ec4ea7b3401aba48ed11aa,
title = "IL-7 Immunotherapy in a Nonimmunocompromised Patient With Intractable Fungal Wound Sepsis",
abstract = "A nonimmunocompromised patient developed life-threatening soft tissue infection with Trichosporon asahii, Fusarium, and Saksenaea that progressed despite maximum antifungal therapies and aggressive debridement. Interleukin-7 immunotherapy resulted in clinical improvement, fungal clearance, reversal of lymphopenia, and improved T-cell function. Immunoadjuvant therapies to boost host immunity may be efficacious in life-threatening fungal infections.",
keywords = "Trichosporon, fungal infection, immunotherapy, interleukin-7, wound infection",
author = "Turnbull, {Isaiah R.} and Mazer, {Monty B.} and Hoofnagle, {Mark H.} and Kirby, {John P.} and Leonard, {Jennifer M.} and Carlos Mejia-Chew and Andrej Spec and Jane Blood and Miles, {Sydney M.} and Ransom, {Eric M.} and Potter, {Robert F.} and Gaut, {Joseph P.} and Remy, {Kenneth E.} and Hotchkiss, {Richard S.}",
note = "Funding Information: This work was supported by the National Institute of Health, National Institute of General Medical Sciences (R35-GM126928 and R35-GM133756). Publisher Copyright: {\textcopyright} 2021 The Author(s).",
year = "2021",
month = jun,
day = "1",
doi = "10.1093/ofid/ofab256",
language = "English",
volume = "8",
journal = "Open Forum Infectious Diseases",
issn = "2328-8957",
number = "6",
}