Abstract
IL-4 has been extensively studied in the context of its role in immunity. Accumulating evidence indicates, however, that it also plays a critical role in higher functions of the normal brain, such as memory and learning. In this review, we summarize current knowledge of the basic immunology of IL-4, describe how and where this cytokine appears to operate in normal brain function, and propose a hypothesis concerning its potential role in neurological pathologies.
| Original language | English |
|---|---|
| Pages (from-to) | 4213-4219 |
| Number of pages | 7 |
| Journal | Journal of Immunology |
| Volume | 189 |
| Issue number | 9 |
| DOIs | |
| State | Published - Nov 1 2012 |