Abstract
Background: Tubulointerstitial nephritis (TIN) is typically seen in association with drug exposure and infection or in autoimmune diseases such as Sjogren's syndrome or systemic lupus erythematosis. The recently described IgG4-related systemic diseases can affect many organ systems including the kidney and typically respond to corticosteroid treatment. Case: We present a case of IgG4-related TIN in a patient with concomitant chronic lymphocytic leukemia. To our knowledge, IgG4-related TIN has not been associated with any hematological disorder such as chronic lymphocytic leukemia. Conclusion: We propose that all kidney biopsies with significant plasma cell infiltrate should be stained for IgG4 as response to treatment is common.
Original language | English |
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Pages (from-to) | 1195-1198 |
Number of pages | 4 |
Journal | Journal of Nephrology |
Volume | 26 |
Issue number | 6 |
DOIs | |
State | Published - Nov 1 2013 |
Keywords
- CLL
- IgG-related kidney disease
- Tubulointerstitial kidney disease