IgG4-related disease and isolated retroperitoneal fibrosis: a narrative review

  • Almurtada Razok
  • , M. E. Romero Noboa
  • , F. Sami
  • , K. N. Patolia
  • , S. Tanveer

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Background: Retroperitoneal fibrosis (RPF) can occur due to many etiologies and is categorized into idiopathic and secondary. Etiologies of secondary RPF include medications, autoimmune disease, malignancy, and IgG4-relat-ed disease (IgG4-RD). Although IgG4-RD usually involves multiple systems synchronically including the pancreas, aorta, and kidneys, it can present with isolated RPF without involvement of other organ systems. Caution must be exercised in these instances as the diagnosis should be confirmed based on specific clinical, radiographic, and histopathologic criteria. Such confirmation can affect the work-up and therapeutic approach as treatment with cor-ticosteroids can lead to remission, both clinically and radiographically.

Original languageEnglish
Pages (from-to)155-157
Number of pages3
JournalARP Rheumatology
Volume2
Issue number2
StatePublished - 2023

Keywords

  • Immunosuppressants
  • Lymphocytes
  • Primary care rheumatology
  • Radiology
  • Soft tissue rheumatism

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