IgG "detoxes" the intestinal mucosa

Lars Eckmann; Thaddeus S. Stappenbeck

doi:10.1016/j.chom.2015.05.001

IgG "detoxes" the intestinal mucosa

Lars Eckmann
, Thaddeus S. Stappenbeck

Division of Laboratory and Genomic Medicine

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host & Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by mucosal and translocated neutrophils.

Original language	English
Pages (from-to)	538-539
Number of pages	2
Journal	Cell Host and Microbe
Volume	17
Issue number	5
DOIs	https://doi.org/10.1016/j.chom.2015.05.001
State	Published - May 13 2015

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10.1016/j.chom.2015.05.001

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@article{d580438cf8764193a170d48de2037ba8,

title = "IgG {"}detoxes{"} the intestinal mucosa",

abstract = "Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host \& Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by mucosal and translocated neutrophils.",

author = "Lars Eckmann and Stappenbeck, \{Thaddeus S.\}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = may,

day = "13",

doi = "10.1016/j.chom.2015.05.001",

language = "English",

volume = "17",

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journal = "Cell Host and Microbe",

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TY - JOUR

T1 - IgG "detoxes" the intestinal mucosa

AU - Eckmann, Lars

AU - Stappenbeck, Thaddeus S.

PY - 2015/5/13

Y1 - 2015/5/13

N2 - Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host & Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by mucosal and translocated neutrophils.

AB - Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host & Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by mucosal and translocated neutrophils.

UR - https://www.scopus.com/pages/publications/84929336702

U2 - 10.1016/j.chom.2015.05.001

DO - 10.1016/j.chom.2015.05.001

M3 - Short survey

C2 - 25974292

AN - SCOPUS:84929336702

SN - 1931-3128

VL - 17

SP - 538

EP - 539

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 5

ER -

IgG "detoxes" the intestinal mucosa

Abstract

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