IgG "detoxes" the intestinal mucosa

Lars Eckmann, Thaddeus S. Stappenbeck

Research output: Contribution to journalShort surveypeer-review

2 Scopus citations


Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host & Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by mucosal and translocated neutrophils.

Original languageEnglish
Pages (from-to)538-539
Number of pages2
JournalCell Host and Microbe
Issue number5
StatePublished - May 13 2015


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