TY - JOUR
T1 - IgG "detoxes" the intestinal mucosa
AU - Eckmann, Lars
AU - Stappenbeck, Thaddeus S.
N1 - Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015/5/13
Y1 - 2015/5/13
N2 - Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host & Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by mucosal and translocated neutrophils.
AB - Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host & Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by mucosal and translocated neutrophils.
UR - http://www.scopus.com/inward/record.url?scp=84929336702&partnerID=8YFLogxK
U2 - 10.1016/j.chom.2015.05.001
DO - 10.1016/j.chom.2015.05.001
M3 - Short survey
C2 - 25974292
AN - SCOPUS:84929336702
SN - 1931-3128
VL - 17
SP - 538
EP - 539
JO - Cell Host and Microbe
JF - Cell Host and Microbe
IS - 5
ER -