@article{b71d05d9dfd545e98272c4c4d84366bd,
title = "Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization",
abstract = "Liu et al. isolated 50 escape mutants to 19 monoclonal antibodies targeting the SARS-CoV-2 spike using a VSV-SARS2 chimera. Some mutants (S477N) resist neutralization by multiple mAbs, and others (E484K) are less sensitive to neutralization by convalescent sera. Several mutants exist in clinical SARS2-CoV-2 isolates and thus warrant further study.",
keywords = "ACE2 receptor decoys, COVID-19 vaccines, SARS-CoV-2 escape mutants, convalescent sera, coronaviruses, monoclonal antibodies, receptor-binding domain",
author = "Zhuoming Liu and VanBlargan, {Laura A.} and Bloyet, {Louis Marie} and Rothlauf, {Paul W.} and Chen, {Rita E.} and Spencer Stumpf and Haiyan Zhao and Errico, {John M.} and Theel, {Elitza S.} and Liebeskind, {Mariel J.} and Brynn Alford and Buchser, {William J.} and Ellebedy, {Ali H.} and Fremont, {Daved H.} and Diamond, {Michael S.} and Whelan, {Sean P.J.}",
note = "Publisher Copyright: {\textcopyright} 2021",
year = "2021",
month = mar,
day = "10",
doi = "10.1016/j.chom.2021.01.014",
language = "English",
volume = "29",
pages = "477--488.e4",
journal = "Cell Host and Microbe",
issn = "1931-3128",
number = "3",
}