Identification of a U7snRNA homologue mapping to the human Xq27.1 region, between the DXS1232 and DXS119 loci

Marina Mostardini; Valentina Appierto; Rossana Pergolizzi; Ileana Zucchi; Steven Mumm; Gian Luca Debellis; Luciano Milanesi; Igor B. Rogozin; Ida Biunno

doi:10.1016/S0378-1119(96)00754-8

Identification of a U7snRNA homologue mapping to the human Xq27.1 region, between the DXS1232 and DXS119 loci

Marina Mostardini, Valentina Appierto, Rossana Pergolizzi, Ileana Zucchi, Steven Mumm, Gian Luca Debellis, Luciano Milanesi, Igor B. Rogozin, Ida Biunno

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3 Scopus citations

Abstract

To contribute to the identification and analysis of novel genes, we undertook the study of a cosmid clone in the Xq27 region of human DNA. The cloned fragment was previously observed to have a high number of evolutionarily conserved sequences. In this genomic stretch of DNA we have identified sequence homologous to the U7 RNA gene including its potential regulatory elements. This paper describes the genomic organisation of this gene and its mapping to the Xq27.1 genomic sub-interval between the DXS1232 and DXS119 loci.

Original language	English
Pages (from-to)	221-224
Number of pages	4
Journal	Gene
Volume	187
Issue number	2
DOIs	https://doi.org/10.1016/S0378-1119(96)00754-8
State	Published - Mar 18 1997

Keywords

Histone-encoding genes
Human X chromosome
Minor small nuclear ribonucleoprotein
Nucleotide sequence
RNA 3' processing

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10.1016/S0378-1119(96)00754-8

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title = "Identification of a U7snRNA homologue mapping to the human Xq27.1 region, between the DXS1232 and DXS119 loci",

abstract = "To contribute to the identification and analysis of novel genes, we undertook the study of a cosmid clone in the Xq27 region of human DNA. The cloned fragment was previously observed to have a high number of evolutionarily conserved sequences. In this genomic stretch of DNA we have identified sequence homologous to the U7 RNA gene including its potential regulatory elements. This paper describes the genomic organisation of this gene and its mapping to the Xq27.1 genomic sub-interval between the DXS1232 and DXS119 loci.",

keywords = "Histone-encoding genes, Human X chromosome, Minor small nuclear ribonucleoprotein, Nucleotide sequence, RNA 3' processing",

author = "Marina Mostardini and Valentina Appierto and Rossana Pergolizzi and Ileana Zucchi and Steven Mumm and Debellis, {Gian Luca} and Luciano Milanesi and Rogozin, {Igor B.} and Ida Biunno",

note = "Funding Information: We are grateful to Prof. D. Schlessinger for the helpful comments on the manuscript. We are also grateful to Drs. Poustka and Korn for their help in performing the cDNA selection. This work was supported by funds from CNR, PF. Ingegneria Genetica (Progetto Genoma Umano) U.O. IB and Telethon 1996–1997 to I.Z.",

year = "1997",

month = mar,

day = "18",

doi = "10.1016/S0378-1119(96)00754-8",

language = "English",

volume = "187",

pages = "221--224",

journal = "Gene",

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TY - JOUR

T1 - Identification of a U7snRNA homologue mapping to the human Xq27.1 region, between the DXS1232 and DXS119 loci

AU - Mostardini, Marina

AU - Appierto, Valentina

AU - Pergolizzi, Rossana

AU - Zucchi, Ileana

AU - Mumm, Steven

AU - Debellis, Gian Luca

AU - Milanesi, Luciano

AU - Rogozin, Igor B.

AU - Biunno, Ida

N1 - Funding Information: We are grateful to Prof. D. Schlessinger for the helpful comments on the manuscript. We are also grateful to Drs. Poustka and Korn for their help in performing the cDNA selection. This work was supported by funds from CNR, PF. Ingegneria Genetica (Progetto Genoma Umano) U.O. IB and Telethon 1996–1997 to I.Z.

PY - 1997/3/18

Y1 - 1997/3/18

N2 - To contribute to the identification and analysis of novel genes, we undertook the study of a cosmid clone in the Xq27 region of human DNA. The cloned fragment was previously observed to have a high number of evolutionarily conserved sequences. In this genomic stretch of DNA we have identified sequence homologous to the U7 RNA gene including its potential regulatory elements. This paper describes the genomic organisation of this gene and its mapping to the Xq27.1 genomic sub-interval between the DXS1232 and DXS119 loci.

AB - To contribute to the identification and analysis of novel genes, we undertook the study of a cosmid clone in the Xq27 region of human DNA. The cloned fragment was previously observed to have a high number of evolutionarily conserved sequences. In this genomic stretch of DNA we have identified sequence homologous to the U7 RNA gene including its potential regulatory elements. This paper describes the genomic organisation of this gene and its mapping to the Xq27.1 genomic sub-interval between the DXS1232 and DXS119 loci.

KW - Histone-encoding genes

KW - Human X chromosome

KW - Minor small nuclear ribonucleoprotein

KW - Nucleotide sequence

KW - RNA 3' processing

UR - http://www.scopus.com/inward/record.url?scp=0030894094&partnerID=8YFLogxK

U2 - 10.1016/S0378-1119(96)00754-8

DO - 10.1016/S0378-1119(96)00754-8

M3 - Article

C2 - 9099884

AN - SCOPUS:0030894094

SN - 0378-1119

VL - 187

SP - 221

EP - 224

JO - Gene

JF - Gene

IS - 2

ER -

Identification of a U7snRNA homologue mapping to the human Xq27.1 region, between the DXS1232 and DXS119 loci

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Keywords

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