Identification and cloning of a CD43-associated serine/threonine kinase

Weimin Wang, Vinzenz Link, Jonathan M. Green

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


CD43 is expressed on most hematopoetic cells and has been shown to regulate the activation and adhesion of T cells. We have cloned a serine/threonine kinase that can interact with the cytoplasmic domain of CD43. This protein is expressed in multiple tissues, including lymphoid cells. Analysis of the subcellular localization reveals it to be present in both the nucleus and the cytoplasm of the cell. The identification of this protein suggests that CD43 may mediate its biologic effects through activation of a kinase cascade, resulting in the regulation of cell growth. (C) 2000 Academic Press.

Original languageEnglish
Pages (from-to)34-39
Number of pages6
JournalCellular Immunology
Issue number1
StatePublished - Oct 10 2000


  • CD43
  • Leukosialin
  • Serine/threonine kinase
  • Sialophorin


Dive into the research topics of 'Identification and cloning of a CD43-associated serine/threonine kinase'. Together they form a unique fingerprint.

Cite this