Hypothermia and neonatal encephalopathy

Lu Ann Papile, Jill E. Baley, William Benitz, James Cummings, Waldemar A. Carlo, Eric Eichenwald, Praveen Kumar, Richard A. Polin, Rosemarie C. Tan, Kasper S. Wang, Wanda Denise Barfield, George Macones, Ann L. Jefferies, Erin L. Keels, Tonse N.K. Raju, Jim Couto

Research output: Contribution to journalArticlepeer-review

241 Scopus citations


Data from large randomized clinical trials indicate that therapeutic hypothermia, using either selective head cooling or systemic cooling, is an effective therapy for neonatal encephalopathy. Infants selected for cooling must meet the criteria outlined in published clinical trials. The implementation of cooling needs to be performed at centers that have the capability to manage medically complex infants. Because the majority of infants who have neonatal encephalopathy are born at community hospitals, centers that perform cooling should work with their referring hospitals to implement education programs focused on increasing the awareness and identification of infants at risk for encephalopathy, and the initial clinical management of affected infants.

Original languageEnglish
Pages (from-to)1146-1150
Number of pages5
Issue number6
StatePublished - Jun 1 2014


  • Head cooling
  • Hyperthermia
  • Hypothermia
  • Infant
  • Neonatal encephalopathy


Dive into the research topics of 'Hypothermia and neonatal encephalopathy'. Together they form a unique fingerprint.

Cite this