Hypertrophic cardiomyopathy with preexcitation: Insights from noninvasive electrocardiographic imaging (ECGI) and catheter mapping

Subham Ghosh, Jennifer N. Avari, Edward K. Rhee, Pamela K. Woodard, Yoram Rudy

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Hypertrophic Cardiomyopathy and Preexcitation. Introduction: Fasciculoventricular pathway has been described as an unusual variant of preexcitation. Electrocardiographic imaging (ECGI) is a novel imaging modality for noninvasive electroanatomic mapping of epicardial activation and repolarization. Case: We present a case of an 18-year-old male with hypertrophic cardiomyopathy (HCM) and an electrocardiogram (ECG)-based diagnosis of Wolff-Parkinson-White (WPW) syndrome, who underwent a noninvasive ECGI study to image ventricular activation, followed by an electrophysiology study (EPS). The ECGI electroanatomic isochrone map showed early activation of the epicardial aspect of the atrioventricular (A-V) groove and an aberrant posterior-base-to- apex progression of activation in the left ventricular (LV) epicardium. The EPS showed a likely fasciculoventricular pathway (FVP) without any inducible tachycardia. Conclusion: While FVP has been described before, this is the first report of detailed quantitative three-dimensional characterization of electrical activation sequence of a heart with this type of preexcitation, using a novel noninvasive imaging modality (ECGI). In spite of abnormal ventricular activation, the EPS demonstrated that the FVP is not capable of supporting reentrant supraventricular tachycardia or rapidly conducted atrial fibrillation.

Original languageEnglish
Pages (from-to)1215-1217
Number of pages3
JournalJournal of cardiovascular electrophysiology
Volume19
Issue number11
DOIs
StatePublished - Nov 1 2008

Keywords

  • Electrocardiographic imaging (ECGI)
  • Fasciculoventricular pathway
  • Preexcitation

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