Hyperpolarized ¹³C MR metabolic imaging can detect neuroinflammation in vivo in a multiple sclerosis murine model

Keyphrases

• Advances in Neuroimaging 20%
• Cuprizone Model 20%
• Glycolysis 20%
• High Density 20%
• Hyperpolarized 20%
• Hyperpolarized 13C 20%
• Hyperpolarized 13C MRI 100%
• Hyperpolarized Pyruvate 80%
• Imaging Techniques 20%
• In Cancer 20%
• Inflammatory Lesions 20%
• Inflammatory Phenotype 20%
• Lactate 80%
• Metabolic Imaging 100%
• Metabolic Pathways 20%
• Metabolic Reprogramming 20%
• Methods for Assessment 20%
• Mononuclear Phagocytes 100%
• Mouse Model of multiple Sclerosis 20%
• MR Spectroscopic Imaging (MRSI) 80%
• Multiple Sclerosis 100%
• Murine Model 100%
• Neurodegenerative Diseases 20%
• Neuroimaging Techniques 20%
• Neuroinflammation 100%
• Neuroinflammatory Diseases 20%
• Neurological Diseases 20%
• Non-invasive Detection 20%
• Non-invasive Monitoring 20%
• Pyruvate Dehydrogenase 20%
• Pyruvate Dehydrogenase Kinase 4 (PDK4) 20%
• Warburg Effect 20%

Medicine and Dentistry

• Carbon 13 100%
• Cuprizone 10%
• Degenerative Disease 10%
• Glycolysis 10%
• Lactic Acid 40%
• Magnetic Resonance Spectroscopic Imaging 40%
• Malignant Neoplasm 10%
• Metabolic Pathway 10%
• Mononuclear Phagocyte 50%
• Multiple Sclerosis 100%
• Neuroinflammation 100%
• Neurologic Disease 10%
• Pyruvate Dehydrogenase 10%
• Pyruvate Dehydrogenase Kinase 10%
• Pyruvic Acid 40%
• Serositis 10%
• Upregulation 10%
• Warburg Effect 10%

Neuroscience

• Glycolysis 20%
• In Vivo 100%
• Mononuclear Phagocyte 100%
• Multiple Sclerosis 100%
• Nervous System Disorder 20%
• Neurodegenerative Disorder 20%
• Pyruvate Dehydrogenase 20%
• Pyruvate Dehydrogenase Kinase 20%
• Reprogramming 20%
• Spectroscopic Magnetic Resonance Imaging 80%